ey words: The COVID-19 pandemic wreaked substantial physical, social, economic, and emotional havoc on all the stakeholders of the Indian agricultural system. Tapioca, being one of the major crops of south India farmers had suffered at various levels of the pre-farm gate and post-farm gate operations due to the pandemic. A comparative analysis of the COVID-19 impacts in two different tapioca-growing regions of South India i.e., Thiruvananthapuram district of Kerala and East Godavari district of Andhra Pradesh has thrown light on how the pandemic had affected tapioca growers in these regions. The study utilized an ex-post facto research design. A scale was developed to measure the perceived impact of the pandemic on pre-farm gate, post-farm gate operations, socio-psychological, and economic & institutional factors. From the study, it was observed that the tapioca growers of both Kerala and Andhra Pradesh had medium to higher levels of impact due to the pandemic on pre-farm gate operations and post-farm gate operations. In Andhra Pradesh, a large majority of respondents had medium to higher levels of impact on socio-psychological factors due to the pandemic. Regarding the impact on economic and institutional factors, the majority of respondents fell in the medium impact category in both states. Significant differences in the components were observed in both states in the Mann-Whitney U test. Factor analysis was performed to analyze the contribution of the components and sub-components towards the impact of the COVID-19 pandemic and it could be concluded that pre-farm gate operations and post-farm gate operations were the major components in Kerala state and socio-psychological factors and post-farm gate operations were the major components in Andhra Pradesh that were affected the most by the pandemic among the tapioca growers.