The white button mushroom (Agari-cusbisporus ) is very popular throughout the world and is the most important mushroom of commercial significance in India. It can be successfully cultivated in place where the environmental condition is favorable but it is cultivated in north India in winter seasons. the optimum temperature for mycelia growth is 22 o c – 25 o c and that for fruiting body formation 14 o c – 18 o c and a high percentage of relative humidity. Keeping that in view the study was conducted in the Krishi Vigyan Kendra (KVK) Jainagar, Koderma, Jharkhand, India during 2017-18 for analysis of different casing mixture on various parameters such as number of days required for mycelium run and pin head initiation on casing layer, weight of fresh harvested mushroom per bag, number of fruiting per bag, biological efficiency (%) and cost benefit ratio of white button mushroom (Agaricus bisporus ).Three treatments including control with eight replications were taken up. Three Treatments comprised of T0 Garden loam soil (GLS) + Farm yard manures (FYM) (2:1), T1 GLS + FYM + Vermi-compost (VC) (2:1:1), T2 GLS + FYM + slack lime (2:1:1). The current study found that during mushroom cultivation process observations were recorded at the different stages of crop growth on various parameters revealed that minimum days required for mycelium of A. bisporus run in casing layer and appearance of pin head stage(17-25 days), Fresh Weight/ maximum yield (0.94kg/bag), maximum number of fruiting bodies (83.25), biological efficiency (18.21%) and cost benefit ratio 1:2.08 were recorded in GLS + FYM + Vermi -compost (2:1:1) as compared to control and other combinations.